Experimental and Bioinformatic Approaches to Studying DNA Methylation in Cancer
Introduction
Basic informations about DNA meth CpGs diseases with global hypomethylation and promoter hypermethylation. DNA met alters chromatin structure with other epigenetic marks (histones modif, TF etc) –> regulate gene exp
Récemment, GW NGS -> DNA methylation marks dans des régions pauvres en CpGs